An APD bias voltage module with voltage boost and automatic compensation for temperature drift was designed. The module includes a positive feedback oscillator, a high frequency full wave rectifier circuit and a temperature compensator. Positive feedback oscillator is used to achieve DC/AC conversion, and the transformer is used to amplify voltage. High-frequency full-wave rectifier circuit outputs DC high voltage through AC/DC conversion. The temperature compensator automatically compensates the temperature drift of APD by the simulate temperature sensor. The size of the module is 1.7cm×2.7cm, the maximum power consumption is 100mW, the output voltage is continuously adjustable in 0~372V, and the maximum ripple is not more than 0.004%. By adjusting the parameters of components in the module, the bias voltage and temperature compensation can be carried out for any type of APD, and the maximum deviation of bias voltage doed not exceed 0.005%.